Rapid test for the qualitative detection of Hepatitis B surface antigen (HbsAg) in whole blood, serum or plasma. The Hepatitis B – HBsAg Cassette Rapid Test Cassette is a rapid test for the qualitative detection of the presence of HBsAg in whole blood, serum or plasma samples. The test uses a combination of monoclonal and polyclonal antibodies to selectively detect high levels of HBsAg in whole blood, serum or plasma. Viral hepatitis is a systemic disease that primarily involves the liver. Most cases of acute viral hepatitis are caused by hepatitis A virus, hepatitis B virus (HBV) or hepatitis C virus. The complex antigen found on the surface of HBV is called HbsAg. Previous designations include the Australia or Au antigen.1 The presence of HBsAg in whole blood, serum or plasma indicates both acute and chronic active hepatitis B infection. In a typical hepatitis B infection, HBsAg is detectable 2 to 4 weeks before the ALT level becomes abnormal and 3 to 5 weeks before symptoms or jaundice develop. HBsAg has four main subtypes: adw, ayw, adr, and ayr. Due to the antigenic heterogeneity of the determinant, there are 10 major serotypes of the hepatitis B virus. The HBsAg Cassette Rapid Test Cassette is a rapid test for the qualitative detection of the presence of HBsAg in whole blood, serum or plasma samples. The test uses a combination of monoclonal and polyclonal antibodies to selectively detect high levels of HBsAg in whole blood, serum or plasma. The HBsAg Rapid Cassette Test is a qualitative immunoassay using the two-site sandwich method for the detection of solid phase HBsAg in whole blood, serum or plasma.