Breathing simulator BRS 300i

for general care

From the generation of simple sinusoidal patterns as stated in the Ph. Eur. and USP for testing nebulisers and MDIs with a spacer/VHC, to complex user-generated profiles for improving in-vitro in-vivo correlations (IVIVCs), our range of Breathing Simulators can be used across a variety of testing applications and patient physiologies. Similar in design and operation to the BRS 200i, the BRS 300i has a larger volume of 0 mL – 5 L. It also features a maximum flow rate of 240 L/min (free flow) and a maximum acceleration of 25L/s2 (free flow) making it the ideal unit for the testing of MDIs and DPIs for improved IVIVCs. 21 CFR Part 11 compliant Stores and recalls methods Powerful drive system for generating challenging profiles Extensive data output options Seamless integration with the Vertus® III range for automated shake, fire, and flow control in breath profile testing Enhanced features including automatic data backups and report printing for greater efficiency and reliability Technical Specifications Volume: 0 mL to 5 L Frequency: 6 – 60 bpm I:E ratio: Variable Waveforms: Sinusoidal, Square, Triangular, User-defined (flow vs time) Profile: Inhalation and/or Exhalation Start: On inhalation or exhalation stroke / User-defined profiles (flow vs time) User interface: Touchscreen Uses: Limited testing of Nebulisers (Ph. Eur. 2.9.44 and USP and testing MDIs with Spacers/VHCs (USP | Improving IVIVCs for MDIs and DPIs: With DUSA for MDI/DPI (Dose Uniformity) With Impactor and Mixing Inlet (APSD)