Flow tester DUSA

DDUfor nasal aerosolsemi-automatic

Overview
The DUSA interface plate provides a leak-free connection between a standard Dose Uniformity Sampling Apparatus (DUSA) and nasal drug products to ensure complete dose capture during Delivered Dose Uniformity (DDU) testing. It is engineered for integration with automated shake-and-fire systems to support routine, automated nasal DDU workflows.

Key benefits

• Apparatus compliant with USP Chapter <601> and Ph. Eur. 0676
• Facilitates simple, leak-free connection between DUSA and nasal aerosol devices for full dose recovery
• Designed for automation to improve repeatability and throughput in DDU testing

Automation features (when used with Vertus® III/III+)

• Automated nasal spray shaking
• Automated nasal spray actuation
• Automated flow control during sampling
• Automated shot-weight measurement and data capture

Manual testing options
Manual nasal aerosol testing is supported via the Inhaler Testing Workstation (ITW) with a vertical or near-vertical DUSA holder for representative manual DDU tests. A Waste Shot Collector (WSC2) provides vertical fire-to-waste alignment. The Angled Nasal Device Holder (cat. no. 8143) allows selectable firing angles (±45°) for consistent manual device orientation.

Usage and compatibility
The interface plate is intended as part of a complete system for nasal aerosol DDU testing and is compatible with Copley automation equipment such as the Vertus® III/III+ automated shake-and-fire systems and manual ITW configurations. It supports compliance with compendial standards and streamlines integration into automated DDU test sequences.

Related products and systems

• Vertus III / Vertus III+ automated shake and fire systems
• DUSA Shaker™ DTS 100i (for automated DUSA workflows)
• Dose Uniformity Sampling Apparatus for MDIs
• Inhaler Testing Workstation (ITW) and accessories: WSC2, Angled Nasal Device Holder (cat. no. 8143)

Technical specifications

• Complies with: USP Chapter <601> and European Pharmacopoeia (Ph. Eur.) Chapter 0676
• Function: Provides leak-free interface between a standard DUSA and nasal aerosol products to ensure complete dose capture
• Automation compatibility: Integrates with Vertus® III/III+ for automated shaking, actuation, flow control and shot-weight measurement
• Manual compatibility: Usable with ITW with vertical/near-vertical DUSA holder for manual DDU testing
• Accessories: Angled Nasal Device Holder (cat. no. 8143) for selectable firing angles (±45°); Vertical Waste Shot Collector (WSC2) for fire-to-waste alignment
• Intended application: Delivered Dose Uniformity (DDU) testing of nasal aerosols and sprays