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... and possibly PBS-based antibody diluents gives increased background staining and decreased staining intensity. Proprietary reagents from Leica Biosystems or TBS-based wash buffer and diluents are recommended. Disclaimer Akt (Phosphorylated) ...
Leica Biosystems
... Antigen background
Anaplastic large cell lymphoma (ALCL) typically comprises large pleomorphic cells that express CD30 and epithelial membrane antigen (EMA). These tumor cells commonly occur in younger patients and may involve cutaneous and ...
Leica Biosystems
... Antigen background
Alpha-fetoprotein (AFP) is a 70 kDa oncofetal antigen detectable in body fluids. Elevated AFP concentrations have clinical relevance; AFP is normally expressed in fetal liver and is absent in healthy adult tissues. It is expressed ...
Leica Biosystems
... Antigen Background
Alpha-methylacyl-CoA racemase (AMACR), also known as p504s, is a mitochondrial and peroxisomal enzyme involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. AMACR is expressed in normal liver ...
Leica Biosystems
... the IFU for recommended dilutions, incubation times and validated procedures. This antibody has been reported in both
immunohistochemistry (IHC) of Lewy body dementia tissue and Western blot analyses of purified Lewy bodies.
Available ...
Leica Biosystems
... the action of male sex hormones (androgens). The androgen receptor has wide distribution and can be demonstrated by immunohistochemistry in several tissues, e.g. prostate, skin, and oral mucosa. Androgen receptor expression has been reported ...
Leica Biosystems
... Analyte Specific
Reagent statement
Analyte Specific
Reagent. Analytical and performance characteristics are not established. Regulatory status varies by SKU (In Vitro Diagnostic Use; Research Use Only; Analyte ...
Leica Biosystems
... specifications
- Clone: BCL-2/100/D5
- Target pathology area: Hematopathology
- Intended use: Immunohistochemistry (P - HIER)
- Configurations available: Liquid Concentrate; BOND RTU (ready-to-use)
- HD
Leica Biosystems
... been reported in non-Hodgkin lymphomas and are detected in approximately 33–45% of diffuse large B-cell lymphomas. Immunohistochemistry frequently demonstrates Bcl-6 nuclear expression in follicular lymphoma, diffuse large B-cell lymphoma, ...
Leica Biosystems
... , Beta-Catenin functions as a transcription effector in the Wnt signaling pathway. Nuclear localization detected by immunohistochemistry is an indicator of Wnt-pathway activation and is observed in various tumorigenic processes, notably ...
Leica Biosystems