Monoclonal antibody PA0963-U

antibodyfor oncologyfor histopathology

Antigen background
Alpha-fetoprotein (AFP) is a 70 kDa oncofetal antigen detectable in body fluids. Elevated AFP concentrations have clinical relevance; AFP is normally expressed in fetal liver and is absent in healthy adult tissues. It is expressed in a subset of germ cell tumors and frequently in yolk sac tumors.

Disclaimer
Recommended for detection of AFP in normal and neoplastic tissues as an adjunct to conventional histopathology using non-immunologic histochemical stains.

Image caption
Human fetal liver: immunohistochemical staining for Alpha Fetoprotein showing cytoplasmic staining of hepatocytes. Alpha Fetoprotein: clone C3.

Product variants and key attributes

• PA0963-U — 7ml AFP BOND RTU Primary; Clone: C3; Pathology menu: Gynepathology; Configuration: BOND RTU; HD: No; Use: P; Source: Monoclonal; Species: Mouse; Regulatory status: In Vitro Diagnostic Use; Volume: 7ml. Availability: Australia, Canada, New Zealand, Puerto Rico, Trinidad and Tobago, United States.
• AFP-L-CE — 1ml NCL-L-AFP; Clone: C3; Pathology menu: Gynepathology; Configuration: Liquid Concentrate; HD: No; Use: P; Source: Monoclonal; Species: Mouse; Regulatory status: In Vitro Diagnostic Use; Volume: 1ml. Availability (examples): Algeria, Andorra, Argentina, Armenia, Australia, Austria, Bahrain, Bangladesh, Belarus, Belgium, Bosnia and Herzegovina, Brazil, Brunei Darussalam, Bulgaria, Chile, China, Colombia, Cote D'Ivoire, Cyprus, Czech Republic, Denmark, Ecuador, Estonia, Finland, France, French Guiana, Georgia, Germany, Ghana, Greece, Guadeloupe, Guyana, Holy See (Vatican City State), Hong Kong, Hungary, Iceland, India, Iraq, Ireland, Israel, Italy, Japan, Jordan, Kazakhstan, Kenya, Kuwait, Latvia, Lebanon, Libya, Liechtenstein, Lithuania, Luxembourg, Malawi, Malta, Martinique, Mauritania, Mauritius, Mayotte, Mexico, Netherlands, New Caledonia, New Zealand, Nigeria, Norway, Occupied Palestinian Territory, Oman, Pakistan, Paraguay, Philippines, Poland, Portugal, Puerto Rico, Qatar, Reunion, Romania, Russian Federation, Saudi Arabia, Senegal, Slovakia, Slovenia, South Africa, Spain, Sudan, Sweden, Switzerland, Taiwan, Tanzania, Thailand, Togo, Trinidad and Tobago, Tunisia, Turkey, Uganda, Ukraine, United Arab Emirates, United Kingdom, Uzbekistan.
• PA0963 — 7ml AFP BOND RTU Primary (alternate SKU); Clone: C3; Pathology menu: Gynepathology; Configuration: BOND RTU; HD: No; Use: P; Source: Monoclonal; Species: Mouse; Regulatory status: In Vitro Diagnostic Use; Volume: 7ml. Availability (examples): Afghanistan, Algeria, Andorra, Argentina, Armenia, Austria, Bahrain, Bangladesh, Belarus, Belgium, Benin, Bosnia and Herzegovina, Brazil, Brunei Darussalam, Bulgaria, Chile, Colombia, Costa Rica, Cote D'Ivoire, Cyprus, Czech Republic, Denmark, Ecuador, Estonia, Ethiopia, Finland, France, French Guiana, Georgia, Germany, Greece, Guadeloupe, Guyana, Holy See (Vatican City State), Hong Kong, Hungary, Iceland, India, Indonesia, Iraq, Ireland, Israel, Italy, Japan, Jordan, Kazakhstan, Kenya, Kuwait, Latvia, Lebanon, Libya, Liechtenstein, Lithuania, Luxembourg, Malawi, Malta, Martinique, Mauritania, Mauritius, Mexico, Moldova, Morocco, Myanmar, Nepal, Netherlands, New Caledonia, Nigeria, Norway, Occupied Palestinian Territory, Oman, Pakistan, Paraguay, Peru, Philippines, Poland, Portugal, Puerto Rico, Qatar, Reunion, Romania, Russian Federation, Saudi Arabia, Senegal, Serbia, Singapore, Slovakia, Slovenia, South Africa, South Korea, Spain, Sudan, Sweden, Switzerland, Taiwan, Tanzania, Thailand, Togo, Trinidad and Tobago, Tunisia, Turkey, Uganda, Ukraine, United Arab Emirates, United Kingdom, Uzbekistan, Vietnam.
• AFP-L-U — 1ml NCL-L-AFP; Clone: C3; Pathology menu: Gynepathology; Configuration: Liquid Concentrate; HD: No; Use: P; Source: Monoclonal; Species: Mouse; Regulatory status: In Vitro Diagnostic Use; Volume: 1ml. Availability: Canada, Puerto Rico, Trinidad and Tobago, United States.

Documents provided (document types only)

• SDS (Safety Data Sheet)
• IFU (Instructions for Use)

Technical characteristics / specifications

• Clone: C3
• Pathology menu: Gynepathology
• Configuration: BOND RTU or Liquid Concentrate (varies by SKU)
• HD (High Definition): No
• Use: P
• Source: Monoclonal
• Species: Mouse
• Regulatory status: In Vitro Diagnostic Use
• Volume: 7ml (BOND RTU) or 1ml (Liquid Concentrate)