Monoclonal antibody AMACR-L-CE

antibodyimmunohistochemistryliquid

Antigen Background
Alpha-methylacyl-CoA racemase (AMACR), also known as p504s, is a mitochondrial and peroxisomal enzyme involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells), and gall bladder (epithelial cells), and has been observed in lung and colonic epithelia. Expression is granular and cytoplasmic. AMACR expression is also detected in hepatocellular and renal carcinomas, various colon carcinomas (well, moderately and poorly differentiated), and is frequently overexpressed in prostate carcinoma.

Disclaimer
Alpha-Methylacyl-CoA Racemase (AMACR, p504s) is intended for detection of specific antigens in normal and neoplastic tissues as an adjunct to conventional histopathology using non-immunologic histochemical stains.

Image
Human prostatic adenocarcinoma: immunohistochemical staining for AMACR showing characteristic granular cytoplasmic staining of malignant cells. AMACR: clone EPMU1.

Available product presentations

• AMACR-L-CE — 1 ml NCL-L-AMACR (Liquid Concentrate)
• PA0210 — 7 ml AMACR (EPMU1) Bond RTU Primary
• AMACR-L-U — 1 ml NCL-L-AMACR (Liquid Concentrate)
• PA0210-U — 7 ml AMACR (EPMU1) Bond RTU Primary

Technical characteristics / specifications

• Clone: EPMU1
• Pathology menu: Uropathology
• Configurations available: Liquid Concentrate; BOND RTU
• HD (High Definition): No
• Use: P (HIER)
• Source: Monoclonal
• Species: Mouse
• Regulatory status: In Vitro Diagnostic Use
• Volumes: 1 ml (NCL-L-AMACR) and 7 ml (BOND RTU primary)