Antigen BackgroundAndrogen receptor is a member of the superfamily of ligand-responsive transcription regulators. The androgen receptor functions in the nucleus where it is believed to act as a transcriptional regulator mediating the action of male sex hormones (androgens). The androgen receptor has wide distribution and can be demonstrated by immunohistochemistry in several tissues, e.g. prostate, skin, and oral mucosa. Androgen receptor expression has been reported in a diverse range of human tumors (e.g. osteosarcoma), and in prostatic carcinoma androgen receptor expression or mutation may have clinical relevance.
DisclaimerAndrogen Receptor is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
IllustrationHuman skin: immunohistochemical staining for Androgen Receptor. Note the nuclear staining of the epithelial cells. Androgen Receptor: clone AR27
Products / Variants- AR-318-L-CE — 1ml NCL-L-AR-318
- AR-318-L-U — 1ml NCL-L-AR-318
Characteristics / technical specifications- Clone: AR27
- Pathology Menu: Uropathology
- Configuration: Liquid Concentrate
- HD (High Definition): No
- Use: P (HIER)
- Source: Mono
- Species: Mouse
- Regulatory Status: In Vitro Diagnostic Use
- Volume: 1ml
- SKUs / Catalog identifiers: AR-318-L-CE; AR-318-L-U
- Product name / bundled name: 1ml NCL-L-AR-318
- Available attachments listed on site: SDS and IFU (documents provided per variant)