Kidney disease assay kit GS8301S

creatinineNGALurine

NGAL (Neutrophil Gelatinase-Associated Lipocalin), a 25-kDa glycoprotein covalently bound to gelatinase, it is synthesized and secreted by tubular epithelial cells of the proximal and distal segment. In healthy kidneys, it is barely detectable in either plasma or urine. However, in the setting of acute tubular injury, NGAL undergoes rapid and profound up regulation with large increases in both urine and plasma. Distinct from traditional markers of function such as creatinine, this rapid response enables NGAL to identify injured kidney much earlier than was previously possible. Sensitivity The limit of quantitation (lowest concentration for which CV is less than a target of 20%)is 13.28ng/ml. Correlation The correlation of a well-known brand(X) and Gcell(y) is y = 1.0044x +8.3600, R2 = 0.99814. Interference Analytes Concentration Hemoglobin 500 mg/dl Vitamin C 50 mg/dl Direct Bilirubin 30 mg/dl Heparin 500U/ml Intralipid 1500mg/dl Linearity Linearity is up to 4920 ng/ml