The PSA in serum is called total PSA (tPSA), and about 10 ≤ 15% of the PSA is about 85% of the free form of (fPSA), about 90% of which is the binding form of (cPSA). Serum total PSA is recognized as the first choice for the diagnosis of prostate cancer. However, when total PSA is in 4-10ng/mL (diagnostic gray area), it cannot distinguish benign prostatic hyperplasia (BPH) from prostate cancer (prostate cancer). The study found that the proportion of fPSA in gray prostate cancer patients was lower than that in benign prostatic hyperplasia (BPH). Therefore, the determination of fPSA concentration and the calculation of the ratio of fPSA to tPSA concentration can improve the diagnostic ash area. Sensitivity and specificity of prostate cancer [1 ≤ 3].
Sensitivity
For analysis sensitivity, the absorbance change rate (△A/min) should more than 0.01 under sample concentration of 2.00 ng/ml.
Correlation
The correlation of a well-known brand(X) and Gcell(Y) is y = 0.8808x + 0.1842, R² = 0.9808
Interference
Analytes
Concentration
Bilirubin
40 mg/dl
Hemoglobin
500 mg/dl
Intralipid
200 mg/dl
RF
100 IU/ml
Linearity
Linearity is [0.30, 10.00] ng/ml.