PSA is localized in the cytoplasm of prostate acinar cells, ductal epithelium and in the secretion on the ductal lumina, present in normal, benign hyperplastic and malignant prostate tissues as well metastatic prostate cancer and in seminal plasma. An elevation of the serum concentration is reported in patients with both benign prostatic hypertrophy Prostate carcinoma, but rarely in healthy men and is absent in normal women.
Serial measurement of PSA concentration in the serum is an important tool in monitoring patients with prostate cancer and determining the potential and actual effectiveness of surgery or other therapies or may allow for earlier discovery of residual or recurrent carcinoma after radical prostatectomy or radiotherapy.
Sensitivity
For analysis sensitivity, the absorbance change rate (△A/min) should more than 0.1000 under sample concentration of 25ng/mL.
Correlation
The correlation of a well-known brand(X) and Gcell(Y) is y = 0.8604x + 0.0262, R² = 0.9866
Interference
Analytes
Concentration
Bilirubin
18.9 mg/dl
Hemoglobin
490 mg/dl
Lipermia
1900
RF
500 IU/ml
Linearity
Linearity up to 100ng/ml.