The fructosamine are formed in blood from glucose present therein. The carbonyl group of the glucose reacts with free protein amino residues causing the formation of Schiff's base. The half life time of the fructosamine is 17-20 days. So fructosamine determination is suitable for a long-term (1-3 weeks) monitoring of sugar metabolism for patients with diabetes, especially with type Ⅱ diabetes mellitus, and also suitable for drug efficacy monitoring.
Sensitivity
For analysis sensitivity, the absorbance change rate (△A/min) should more than 0.0200 under sample concentration of 290µmol/L.
Correlation
The correlation of a well-known brand(X) and Gcell(Y) is y = 0.7729x + 62.756, R² = 0.8439
Interference
Analytes
Concentration
Direct Bilirubin
30 mg/dl
Hemoglobin
2000 mg/dl
Intralipid
667 mg/dl
VC
10mg/dl
Glucose
50 mmol/l
Linearity
Linearity up to 1000μmol/L.