Automated filling machine XTREMA PWD Series

fully-automaticintermittent-motionvacuum

Product overview
The XTREMA PWD Series is a compact, high-speed powder micro-dosing and stoppering system engineered for aseptic pharmaceutical processing. It enables dosing of multiple powders into the same vial with separate 100% check-weighing (SPLIT-FILL) and is designed for low-fill microdosing, high containment and a small footprint.

Key functional features

• Vacuum–pressure filling principle with positive intermittent in-line vial transport.
• Capability to dose up to three distinct powders into a single vial (split-fill workflow with separate 100% check-weighing per powder).
• Compact automation architecture providing high automation level in reduced floor space.
• 100% in-process control (IPC) at full production speed (up to 400 vials per minute) including tare/gross/gross check-weighing.
• Containment via cRABS (controlled Restricted Access Barrier System) with recirculating Laminar Air Flow (LAF) and regulated temperature and humidity.
• Continuous stoppering unit integrated with powder handling and gas purging steps prior to stoppering.

Technical data
Min. | Max.
Vial diameter: 22 | 56
Vial height: 30 | 136
Stopper diameter: 20 | 33
Stopper height: – | 25
Powder dosing unit: Up to 3 dosing units
Filling volume: From 10 mg
Output with 100% IPC: Up to 400 vpm
Transport system: Intermittent motion

Machine highlights

• Consolidated vacuum–pressure filling combined with positive intermittent vial transport for precise low-volume fills.
• Up to three independent dosing units enabling individual filling of different powders into the same vial.
• Integrated 100% IPC running at production speed (up to 400 vpm) including tare and gross checks.
• High-containment solution: cRABS with recirculating LAF and environmental control (temperature and humidity).
• Continuous stoppering with pre-stoppering gas purging and integrated powder management.

Characteristics / technical specifications

• Model family: XTREMA PWD Series.
• Brand: IMA.
• Vial diameter range: 22 mm – 56 mm.
• Vial height range: 30 mm – 136 mm.
• Stopper diameter range: 20 mm – 33 mm; stopper maximum height: 25 mm.
• Powder dosing units: up to 3 units (capable of dosing up to 3 different powders into the same vial).
• Minimum filling volume: from 10 mg (microdosing capability).
• Output (with 100% IPC): up to 400 vials per minute.
• Transport system: intermittent motion (positive intermittent in-line vial transport).
• Filling principle: consolidated vacuum–pressure filling.
• Containment and environmental control: cRABS with recirculating Laminar Air Flow, controlled temperature and humidity.
• Stoppering: continuous stoppering unit with gas purging capability prior to stoppering.
• Inspection/quality control: integrated 100% check-weighing (IPC) including tare/gross/gross as part of the process; supports SPLIT-FILL workflow for separate check-weighing of differing powders in the same vial.
• Footprint: compact design for high automation with reduced floor space.