Automatic dissolution tester SDT-L Offline

fully-automaticfor the pharmaceutical industryfor tablets

Product overview
SDT-L Offline is a comparative dissolution system designed to test two formulations simultaneously in a single instrument using 12–14 vessels. The compact configuration ensures identical test conditions for both formulations, reduces equipment footprint and operational time, and supports bioequivalence and biowaiver studies. Integrated automated sampling and advanced control features enable repeatable, reproducible and compliant dissolution testing.

Key benefits

• DUAL TESTING - Enables head-to-head bioequivalence and biowaiver studies of generic versus innovator formulations.
• EFFICIENCY - Reduces equipment requirements, operator time and overall cost for comparative dissolution workflows.
• REPRODUCIBILITY - Automated simultaneous sampling captures samples at precise times and volumes.
• REPEATABILITY - Single-instrument setup maintains identical test conditions across both formulations for GMP environments.
• COMPLIANCE - Facilitates regulatory compliance with built-in SOTAX AutoCompliance™ features.
• CLEANING - Automated end-of-test wash routines minimize carry-over between runs.
• FLEXIBILITY - Configurable sampling options to match existing laboratory setups for maximal comparability.

Highlights

• Comparative testing: Designed to run two formulations simultaneously in one instrument, ensuring identical test conditions and streamlined comparative workflows.
• Space-saving design: Compact oval bath with integrated syringe pumps and an improved layout for visibility of vessel positions. Optional CenterView™ video monitoring records dissolution for each vessel individually.
• Efficient repeatability: Fully automated sampling removes operator variability; withdrawn volumes are automatically replaced; up to 15 timepoints supported per run.
• User-friendly operation: Intuitive EasyTouch™ interface with pre-programmed methods, icon-based navigation, and network PDF reporting for efficient documentation.
• Automated sampling: High-precision syringe pumps sample simultaneously from 12–14 vessels; sampling volumes 1–10 mL; samples collected in glass tubes or capped LC vials; up to 15 timepoints.
• AutoCompliance™: Self-centering vessels, fixed shaft height and quick-lock mechanism to support compliance with USP 711, USP 724, Ph.Eur. 2.9.3/2.9.4 and other harmonized pharmacopoeias.

Modules / Options

• SDT-L dissolution tester: Dissolution bath configured for 12–14 vessels for comparative testing.
• SFC-SR sample manager: Integrated sample collector providing high flexibility and accurate fraction collection.
• Optional CenterView™ video monitoring for individual vessel visualization and documentation.

Technical characteristics / specifications

• Number of vessels: 12–14 (comparative testing configuration).
• Sampling: Integrated high-precision syringe pumps with 5 mL syringes; simultaneous sampling from all vessels.
• Sampling volumes: 1–10 mL (automatically selectable).
• Timepoints: Up to 15 timepoints per test.
• Sample containers: Glass tubes or capped LC vials.
• Volume handling: Withdrawn volumes automatically replaced to maintain test conditions.
• Design: Compact oval bath layout for minimal bench footprint and improved visibility.
• Compliance features: AutoCompliance™ (self-centering vessels, fixed shaft height, quick-lock); meets relevant USP/Ph.Eur./BP/JP harmonized requirements.
• User interface: EasyTouch™ intuitive operation, pre-programmed methods, icon navigation, network printing and PDF reporting to file share.
• Cleaning: Automated end-of-test washing routines to prevent carry-over.
• Optional features: CenterView™ video monitoring; flexible sampling options to match laboratory environments.