Automatic dissolution tester ATS Xtend™ Double UV On-/Offline

for the pharmaceutical industryfor tabletsfor capsules

Product Overview
Share your fraction collector and UV-Vis for online testing and offline collection with your dissolution testers. The ATS Xtend™ Double UV On-/Offline system allows sharing one UV-Vis spectrophotometer and one dual-rack sample collector between two dissolution baths to double throughput while minimizing footprint.

Key Benefits

• THROUGHPUT - Double your capacity and perform two dissolution tests in parallel with one UV-Vis and sample collector.
• FLEXIBLE - Alternate between UV-Vis online analysis and offline collection without system modification.
• SPACE - Minimize footprint by stacking the UV-Vis on two pump modules.
• ONLINE - Single or multi-wavelength analysis from up to 16 vessels simultaneously.
• ANALYZE - High-precision double beam UV-Vis technology (CDD) with reference compensation for accurate measurement.
• OFFLINE - Collect dissolution samples from 16 vessels in glass tubes, capped LC vials, or well plates.
• COMPLIANCE - Fully compliant with Pharmacopeia requirements and 21 CFR part 11.

Automation
The ATS Xtend™ automates key steps of the dissolution test to reduce variability and increase laboratory productivity. Features include automated vessel filling and cleaning, repeatable sampling positions, controlled pulling force, precise withdrawn volumes and timing, and automated filtration to ensure highly reproducible dissolution results.

Highlights

• Up to 16 vessels: When sampling from two Xtend™ dissolution baths simultaneously, one UV-Vis and a dual-rack sample collector handle samples withdrawn automatically filtered and either analyzed online or collected offline.
• No waiting times: Immediate parallel analysis of up to 16 samples at each sampling point with protocolled UV-Vis results and combined reporting; uses double beam UV-Vis technology (CDD) with reference compensation.
• Fine filtration: Flexible sampling and filtration options including cannula filters, disc filters, and syringe filters; supports fine filtration down to 0.2 µm for offline HPLC/UPLC workflows.
• Simplified scale-up: Add a second dissolution bath and pump to increase capacity; identical components simplify validation while shared UV-Vis and dual-rack collector save bench space and investment.

Modules (examples)

• AT dissolution tester - Xtend™ dissolution bath with flexible sampling & monitoring functions.
• CP piston pump - Benchtop piston pump for pumping through filters and handling foaming media.
• Specord® UV-Vis - Double beam spectrophotometer with CDD for real-time dissolution data.
• SAM-S sample manager - Dual-rack sample manager to collect samples from two dissolution testers.
• WinSOTAX®plus - Dissolution software to manage methods, results and reports with 21 CFR part 11 capabilities.

Options (examples)

• FS filter station - Automated change of syringe filters for multi-timepoint methods (DR/MR).
• CenterView™ - Video monitoring of the dissolution process in each vessel.
• MPS media station - Mobile media preparation station to heat, degas and dispense media.
• q-doc® software - Data management solution with integrated 21 CFR part 11 compliance.

Specifications

• Model: ATS Xtend™ Double UV On-/Offline.
• Analysis: Single or multi-wavelength UV-Vis online analysis; double beam UV-Vis (CDD) with reference compensation.
• Vessels supported: Up to 16 vessels per system (parallel sampling/analysis).
• Sampling modes: Online analysis (UV-Vis) or offline collection (glass tubes, capped LC vials, well plates).
• Throughput: Capable of running two dissolution baths in parallel sharing one UV-Vis and one dual-rack sample collector.
• Filtration: Supports cannula filters, disc filters, syringe filters; fine filtration down to 0.2 µm.
• Automation: Automated vessel filling, emptying and system cleaning; repeatable sampling positions, controlled withdrawal volumes and timing, automated filtration.
• Compliance: Designed to meet pharmacopoeia requirements and 21 CFR part 11 data integrity standards (software integration available).
• Integration: Compatible modules include AT dissolution bath, CP piston pump, Specord® UV-Vis, SAM-S sample manager, WinSOTAX®plus, FS filter station, CenterView™, MPS media station, q-doc®.
• Software & Data: Integration with WinSOTAX®plus for method control, results and reporting; q-doc® available for broader data management and compliance.