Sabervet Canine Heartworm Antigen/Ehrlichia/Babesia Gibsoni/Anaplasma Antibody Combo Rapid Test sold by Antigenne is a lateral flow immunoassay intended for the simultaneous qualitative detection of specific antibodies from Canine Ehrlichia(EHR) and Babesia Gibsoni(BG) and Anaplasma(ANA) and specific antigens from canine Heartworm (CHW) in Whole Blood or Serum or Plasma samples.
Description
Pathology Description
Adult canine heartworm parasites are found primarily in the pulmonary artery and right ventricle and, in severe infections, in the right atrium, anterior and posterior vena cava, and pulmonary artery. The adult worms are elongated and white. The severity of clinical signs depends on the duration and extent of infection and the host’s response to the worms.
The main symptoms in dogs are coughing, decreased training endurance and weight loss. Other symptoms include palpitations, murmurs in the heart, dyspnoea, elevated body temperature and increased abdominal circumference. In the later stages, anaemia is enhanced and death occurs by gradual emaciation and debilitation.
In vena cava syndrome, a large number of worms in the right atrium and vena cava can cause sudden collapse and death. This is often preceded by loss of appetite and jaundice. Dogs with malarial filariasis often have a nodular skin disease characterised by itching and multiple nodules that tend to break down. The centres of the skin nodules are suppurating and microfilariae are commonly found in the blood vessels surrounding them.