Rapid leishmaniasis test SaberVet

veterinaryfor dogsLeishmania

The SaberVet Canine Leishmania Antibody Rapid Test sold by Antigenne is a lateral flow immunoassay intended for the qualitative detection of specific antibody from canine Leishmania (C.LSH) in canine serum, plasma or whole blood samples. The test is useful for determination of C.LSH infection.It is recommended for dogs with weight loss, polyuria, polydipsia, muscle atrophy, depression, vomiting, diarrhea and other symptoms. Description Pathological Introduction Transmission and Infection Canine Leishmania (Leishmania spp.) is a parasitic protozoan parasite that is transmitted primarily after the the bite of sandflies (Phlebotomus spp.). Dogs are one of the main hosts of Leishmania spp. Leishmania spp. reproduce in macrophages in dogs and cause canine leishmaniasis (Leishmaniasis). Pathologic process Following Leishmania infection, the protozoa proliferate within macrophages in dogs, causing cell rupture and release of the protozoa, which then infect additional cells. Major pathologic changes include: Cutaneous type: manifests as skin ulcers, alopecia, skin nodules and ulceration. Visceral form: causes systemic disease involving several internal organs such as the liver, spleen, lymph nodes and bone marrow. Clinical symptoms Skin symptoms: hair loss, skin ulcers, increased dandruff, skin nodules and itching. Systemic symptoms: weight loss, loss of appetite, weakness, fever, enlarged lymph nodes, enlarged liver and spleen. Other symptoms: joint pain, swollen limbs, eye inflammation (e.g., conjunctivitis, keratitis).