Peptide synthesis platform Syro I

robotizedhigh-throughput

Overview
Fully automated parallel peptide synthesizers designed for high-throughput peptide synthesis. Modular and scalable systems integrating Syro XP software for instrument control, protocol management and reagent calculation. Suitable for research and production laboratories requiring flexible synthesis formats.

Main benefits

• Complete system package including desktop PC, flat panel monitor and printer supplied with Syro XP software
• Syro XP software controls instrument functions, calculates amino acid and reagent requirements and allows unique protocols per synthesis cycle
• Flexible reactor block formats (12–96 positions) enabling scalable throughput
• 3-tip wash comb for efficient washing and dispensing from external bottles
• Digital syringe pumps for microliter-accurate reagent dispensing and reduced waste
• Variable-speed vortex mixing to optimize mixing, yield and purity

System variants

• Syro I: single-arm pipetting robot with one reactor block as standard; expandable with a 96-position tip reactor block
• Syro II: dual-arm pipetting robot with two reactor blocks as standard; expandable with up to six 96-position tip reactor blocks for high-throughput applications

Scales and formats
Reactor blocks available from 12 to 96 positions. Optional heating and reaction vessels ranging from 0.4 mL to 20 mL support synthesis scales from 1 to 600 μmol per vial.

Additional features

• Dedicated digital syringe pumps: separate pumps for amino acids and for solvents/reagents
• Amino acid rack capacity and reagent bottle racks sized for automated operation (amino acid rack: 40 × 50 mL)
• Integrated vacuum pump (model dependent on system)
• Certifications: CE, cTÜVus

Technical specifications

• Footprint (W × D × H): Syro I: 56 × 70 × 91 cm; Syro II: 82 × 70 × 91 cm
• Weight: Syro I: 60 kg; Syro II: 85 kg
• Automation: single robotic arm (Syro I) or dual robotic arm (Syro II) with triple pipetting wash comb
• Liquid handling: digital syringe pumps (2 × 5 mL; 1 × 5 mL for amino acids; 3 × 10 mL for solvent wash and reagents)
• Mixing: vortex mixer for one or two reactor blocks
• Equipment included: desktop PC, flat panel monitor, printer and Syro XP software
• Robot power requirements: EU: 230 V~, 50 Hz (1.9 A); USA: 120 V~, 60 Hz (4.4 A); Japan: 100–115 V~, 50/60 Hz (5.0 A) (Fuse: GDC 5.0A/250VAC)
• Vacuum pump models: Syro I: ME 2C; Syro II: ME 4C
• Vacuum pump power: EU: 230 V~, 50 Hz (1.8 A); USA: 120 V~, 60 Hz (3.4 A); Japan: 100 V~, 50/60 Hz (3.4 A) (Fuse: F 4.0A/250VAC)
• Reactor block details: Syro I: one U-type block for 2, 5 and 10 mL vials (24 or 48 positions); Syro II: two U-type U-blocks for 2, 5 and 10 mL vials (24 or 48 positions)
• Amino acid rack capacity: 40 × 50 mL
• Reagent bottle racks: Syro I: 2 × 500 mL, 3 × 200 mL; Syro II: 3 × 500 mL, 4 × 200 mL
• Waste bottle: 1 × 10 L Nalgene bottle