Robotized synthesis platform Initiator+

microwavemanualhigh-throughput

Product overview
Biotage® Initiator+ is a microwave synthesizer platform for fast, reproducible organic synthesis. It supports manual operation and is upgradable to Robot Eight (8 vials) or Robot Sixty (60 vials) automation to match throughput requirements. The system provides rapid heating, controlled pressure handling and flexible vial formats for lab-scale workflows from milligrams to grams.

Key benefits

• Rapid, reproducible microwave heating to shorten reaction times and reduce solvent use.
• Modular upgradeability: manual use to 8- or 60-position automation for higher throughput.
• Large integrated 10.4" touchscreen with Biotage Wizard for guided setup without external PC, keyboard or mouse.
• Fast heating up to 300 °C (ramp depends on solvent and power).
• Supports four vial sizes for scalable reactions from milligrams to grams.
• Triple-tier safety lock and explosion-rated containment for operator protection; high-grade aluminum construction.
• Capability for higher reactant concentrations to minimise waste.

Operation and interfaces

• On-board computer with 10.4" diagonal touchscreen and step-by-step guidance.
• Archiving and backup via USB; printing via Ethernet LAN.
• No external PC required; complex methods can be run from the integrated interface.

Applications & suitability

• Multi-user laboratories, library synthesis and scale-out workflows where queuing and hands-free operation are advantageous.
• Lab-scale synthesis from milligram to gram scale with flexible vial formats and automation options.

Specifications / Technical data

• Reaction volumes: 0.2–20 mL
• Temperature range: 40–300 °C
• Pressure range: 0–30 bar (0–3 MPa; up to ~435 psi)
• Power range: 0–400 W (magnetron) at 2.45 GHz
• Upgradability: Robot Eight (8 vials) and Robot Sixty (60 vials); rack capacities — large racks: 2x2 or 2x12 vials; small racks: 2x4 or 2x30 vials.
• Interfaces: on-board computer with 10.4" touchscreen; USB for archive/backup; Ethernet LAN for printing.
• Reaction time: up to 96 hours maximum; typical irradiation 2–15 minutes.
• Heating rate: typically 2–5 °C/s depending on solvent and power.
• Agitation: variable magnetic stirring, 300–900 RPM.
• Cooling / pressurised air supply: >60 L/min, 2.5–4.0 bar (0.25–0.40 MPa; 36–58 psi)
• Electrical supply: 100–120 VAC or 220–240 VAC, 50/60 Hz. Connect only to a grounded outlet.
• Max power consumed: 1100 VA
• Weight: 21 kg (48.5 lbs)
• Dimensions (W x D): 365 x 422 mm; Height: 421 mm
• Max sound level: 70 dB(A)
• Ports: Ethernet LAN (IEEE 802.3), USB 3.0
• Certificates: CE, CSA
• Operating ambient temperature: 18–32 °C; Storage/transportation temperature: -25 °C to 60 °C
• Humidity: 20–95% RH (non-condensing)