ProductISOLUTE® HM-N — modified diatomaceous earth cartridges and bulk media for solid-supported extraction and trace water removal from organic solvents
OverviewISOLUTE® HM-N enables cleanup prior to analysis of lipophilic compounds in complex biological matrices and provides efficient removal of water-soluble impurities from reaction mixtures. It supports dry loading workflows for flash purification and is used for trace water removal from water-immiscible organic solvents.
Key benefits and applications- Supports dry loading for flash purification.
- Removal of water-soluble impurities from reaction mixtures.
- Removal of trace water from water-immiscible organic solvents.
- Solid-supported liquid-liquid extraction to prevent emulsion formation and ensure reproducible phase separation.
- Alternative to a separating funnel for routine liquid-liquid extraction and a practical method for sample drying.
Performance noteWhen removing trace water from water-immiscible solvents, ISOLUTE® HM-N has a maximum adsorption capacity of approximately 750 µL water per gram; actual capacity varies with solvent.
Ordering information- 800-0040-BM | ISOLUTE® HM-N 0.3 mL Sample | 100 | Get a quote
- 800-0040-BMG | ISOLUTE® HM-N 0.3 mL Sample (Tabless) | 100 | Get a quote
- 800-0100-CM | ISOLUTE® HM-N 1 mL Sample | 100 | Get a quote
- 800-0100-CMG | ISOLUTE® HM-N 1 mL Sample (Tabless) | 100 | Get a quote
- 800-0220-DM | ISOLUTE® HM-N 3 mL Sample | 100 | Get a quote
- 800-0350-EM | ISOLUTE® HM-N 5 mL Sample | 100 | Get a quote
- 800-0700-FM | ISOLUTE® HM-N 10 mL Sample | 50 | Get a quote
- 800-1300-FM | ISOLUTE® HM-N 20 mL Sample | 50 | Get a quote
- 9800-0025 | ISOLUTE® HM-N Bulk 25 g | 1 | Get a quote
- 9800-0500 | ISOLUTE® HM-N Bulk 500 g | 1 | Get a quote
- 9800-1000 | ISOLUTE® HM-N Bulk 1 Kg | 1 | Get a quote
- 9800-5000 | ISOLUTE® HM-N Bulk 5 Kg | 1 | Get a quote
- 9800-10000 | ISOLUTE® HM-N Bulk 10 Kg | 1 | Get a quote
Resources (selected)- Technical note: The use of ISOLUTE® HM-N for rapid sample preparation
- Product note: QuickStart guide to SPE
Technical specifications- Brand: Biotage
- Denomination: ISOLUTE® HM-N
- Material: Modified diatomaceous earth (supported media)
- Product form: Prepacked cartridges (0.3–20 mL) and bulk media (25 g–10 kg)
- Available sample cartridge volumes: 0.3 mL, 1 mL, 3 mL, 5 mL, 10 mL, 20 mL
- Bulk formats: 25 g, 500 g, 1 kg, 5 kg, 10 kg
- Typical pack sizes: cartridges commonly in packs of 100; some larger cartridges in packs of 50; bulk formats single unit
- Maximum adsorption capacity for water (approximate): 750 µL water per gram (varies with solvent)
- Primary applications: dry loading for flash purification, water removal from organic solvents, removal of water-soluble impurities, solid-supported liquid-liquid extraction, SPE clean-up for lipophilic compounds