Flash chromatography system Flash 75

for productionfor research and developmentmodular

Overview
Flash chromatography systems for process development and manufacturing. Designed to enable reproducible scale-up from laboratory methods to production-scale purification. Both systems operate safely at 100 psi, permitting high flow rates and the use of higher-viscosity solvents. Proven patented radial compression technology minimizes "wall effects" and channeling inside each column, preserving bed stability and delivering cleaner fractions with improved overall yield.

Key benefits and performance

• Safe, reliable scale-up: operate at 100 psi to achieve fast flow rates and accommodate viscous solvent systems.
• Radial compression technology: minimizes wall effects and channeling for enhanced bed stability and higher purity and recovery.
• Time efficiency: up to 80% time savings compared with traditional glass columns in comparable workflows.
• Biotage® Flash 150: handles up to 500 g samples at flow rates up to 1 L/min; demonstrates up to 4× recovery versus glass columns in validated conditions.
• Biotage® Flash 75: handles up to 100 g samples at flow rates up to 250 mL/min with fewer mixed fractions than glass columns, improving product purity.

Your complete kit

• Radial compression module (easy-to-install) included with Flash 150 system.
• Fully integrated gas manifold and solvent reservoir.
• Sample injection module (SIM).
• Start-up kit with required tubing and fittings.
• Grounding kit for safe inert-gas operation.
• User's manual included.

Ordering information (table)

• SF-022-25151 — Flash 150L system — 1 — Get a quote
• SF-022-25071 — Flash 150M system — 1 — Get a quote
• SF-022-19071 — Flash 75L system — 1 — Get a quote
• SF-022-19041 — Flash 75M system — 1 — Get a quote
• SER-150-IN — Installation and Familiarization - Biotage® Flash 75/150 — 1 — Get a quote
• SER-150-IQOQ — Qualification Package - IQ/OQ - Biotage® Flash 75/150 — 1 — Get a quote

Literature & resources (available documents)

• Scalable flash purification - From development to production (brochure)
• Selection guide: Scale-up and method development resources
• White paper: Optimizing chromatographic purification for rapid results in chemical manufacturing

Notes
Systems are modular with variable footprints depending on configuration and options. Solvent delivery is via an inert gas–pressurized solvent tank; the systems are inert-gas driven and fully grounded, requiring no electrical power for solvent delivery.