Monoclonal antibody PA0424-U

for histopathologydiagnostictissue

Antigen background
CA19-9 is an epitope on the sialylated Lewisa carbohydrate structure. Sialyl Lewisa contributes to cell adhesion by acting as a ligand for the inducible adhesion molecule E‑selectin. CA19-9 and CA50 are established serum and tissue markers used in the evaluation and follow-up of gastrointestinal and pancreatic neoplasms; expression level often correlates with tumor differentiation. Both markers may also be detected in certain benign pancreatic lesions, such as chronic pancreatitis.

Product specific information
Clone C241:5:1:4 reacts specifically with Sialyl Lewisa-containing glycolipids with no cross‑reaction to Lewisa, Lewisb or other related structures. The epitope recognized by NCL-L-CA19-9 is designated CA19-9. Available configurations include ready-to-use BOND RTU formats and a liquid concentrate variant.

Disclaimer
CA19-9 (Sialyl Lewisa) reagents are intended for detection of specific antigens in normal and neoplastic tissues as an adjunct to conventional histopathology and should be interpreted in the context of clinical and other laboratory findings.

Available product configurations

• PA0424-U — 7ml CA19-9 Bond RTU Primary: Configuration: BOND RTU; Volume: 7 ml; Regulatory Status: In Vitro Diagnostic Use; Use: P (HIER); Source: Mono; Species: Mouse; Clone: C241:5:1:4; Pathology Menu: Gastrointestinal Pathology; HD: No.
• CA19-9-L — 1ml NCL-L-CA19-9 (Liquid Concentrate): Configuration: Liquid Concentrate; Volume: 1 ml; Regulatory Status: Research Use Only; Use: P (HIER); Source: Mono; Species: Mouse; Clone: C241:5:1:4; Pathology Menu: Gastrointestinal Pathology; HD: No.
• PA0424 — 7ml CA19-9 Bond RTU Primary: Configuration: BOND RTU; Volume: 7 ml; Regulatory Status: In Vitro Diagnostic Use; Use: P (HIER); Source: Mono; Species: Mouse; Clone: C241:5:1:4; Pathology Menu: Gastrointestinal Pathology; HD: No. (This item replaces CALP.)

Technical characteristics / specifications

• Clone: C241:5:1:4
• Pathology menu: Gastrointestinal Pathology
• Configuration: BOND RTU (ready-to-use) and Liquid Concentrate (variant CA19-9-L)
• HD (High Definition): No
• Use: P (HIER)
• Source: Monoclonal
• Species: Mouse
• Regulatory status: In Vitro Diagnostic Use (BOND RTU variants); Research Use Only (Liquid Concentrate variant)
• Volumes and SKUs: PA0424-U — 7 ml (BOND RTU); PA0424 — 7 ml (BOND RTU); CA19-9-L — 1 ml (Liquid Concentrate)