Antibody CALRET566-L-CE

monoclonal antibodydiagnosticimmunohistochemistry

Antigen background
Calretinin is a 29 kD calcium-binding protein of the EF-hand family, abundantly expressed in neurons and present in various non-neuronal cell types including mesothelial cells, steroid-producing cells (adrenal cortical cells, Leydig cells, ovarian theca interna cells, Sertoli cells), certain neuroendocrine cells and eccrine sweat glands.

Indications and utility
Anti-Calretinin (clone CAL6) is used as an immunohistochemical marker in diagnostic pathology. It is particularly useful as an adjunct for distinguishing malignant mesothelioma from carcinoma and for the differential diagnosis of ovarian stromal tumors. Use in combination with other markers and conventional histopathology is recommended.

Products / Variants

• CALRET566-L-CE — 1 ml NCL-L-CALRET-566 (Liquid Concentrate)
• PA0346 — 7 ml Calretinin Bond RTU Primary (BOND RTU)
• CALRET566-L-U — 1 ml NCL-L-CALRET-566 (Liquid Concentrate; United States / Canada availability)
• PA0346-U — 7 ml Calretinin Bond RTU Primary (BOND RTU; United States / Canada availability)

Image caption
Human testes: immunohistochemical staining for calretinin showing cytoplasmic staining of Leydig cells. Calretinin: clone CAL6

Technical specifications

• Clone: CAL6
• Pathology menu: Lung Pathology
• Configuration: Liquid Concentrate or BOND RTU (variant dependent)
• HD (High Definition): Yes
• Use: P (HIER)
• Source: Monoclonal
• Host species: Mouse
• Regulatory status: In Vitro Diagnostic Use
• Available volumes: 1 ml and 7 ml (variant dependent)
• Representative SKUs: CALRET566-L-CE (1 ml), PA0346 (7 ml), CALRET566-L-U (1 ml), PA0346-U (7 ml)
• Replaces: CALRET566-L; CALRET566-L-CE-S; CALRETININ; CALRETININ-CE; CALRETININ-CE-S; CALRETININ-L-CE; CALRETININ-R-7; CALRETININ-R-7-C; CALRETININ-R-7-CE; CALRETININ-S