Antigen backgroundCarcinoembryonic antigen (CEA) is a heterogeneous cell surface glycoprotein produced by fetal colonic cells. Low levels are present on normal adult colonic mucosal epithelia and in various other normal tissues. CEA is encoded by the CEA gene on chromosome 19 and belongs to the CEA gene family within the immunoglobulin superfamily. CEA exhibits cell adhesion properties that, together with other adhesion molecules, influence cell–cell interactions.
DisclaimerRecommended for detection of specific antigens in normal and neoplastic tissues as an adjunct to conventional histopathology using non-immunologic histochemical stains.
Image captionHuman bowel: immunohistochemical staining for CD66e. Note cytoplasmic staining of epithelial cells. CD66e: clone 12-140-10.
Available products / variants- CEA-609-L-CE — 1ml NCL-L-CEA-609; Configuration: Liquid Concentrate; Clone: COL-1; HD (High Definition): Yes; Use: P (HIER); Source: Monoclonal; Species: Mouse; Regulatory status: In Vitro Diagnostic Use.
- PA0848 — 7ml CEA (CD66e) (COL-1) Bond RTU Primary; Configuration: BOND RTU; Clone: COL-1; HD (High Definition): Yes; Use: P (HIER); Source: Monoclonal; Species: Mouse; Regulatory status: In Vitro Diagnostic Use.
- CEA-609-L-U — 1ml NCL-L-CEA-609 (alternate SKU); Configuration: Liquid Concentrate; Clone: COL-1; HD: Yes; Use: P (HIER); Source: Monoclonal; Species: Mouse; Regulatory status: In Vitro Diagnostic Use.
- PA0848-U — 7ml CEA (CD66e) (COL-1) Bond RTU Primary (alternate SKU); Configuration: BOND RTU; Clone: COL-1; HD: Yes; Use: P (HIER); Source: Monoclonal; Species: Mouse; Regulatory status: In Vitro Diagnostic Use.
Replacements- Replaces: CEA-2-L, CEA-2-L-U, PA0004.
Technical characteristics / specifications- Clone: COL-1
- Pathology menu: Gastrointestinal Pathology
- Configuration: Liquid Concentrate or BOND RTU (product-dependent)
- HD (High Definition): Yes
- Use: P (HIER)
- Source: Monoclonal
- Species: Mouse
- Regulatory status: In Vitro Diagnostic Use
- Volume: 1ml or 7ml (depending on SKU)
- Known SKUs / pack options: CEA-609-L-CE (1ml), PA0848 (7ml), CEA-609-L-U (1ml), PA0848-U (7ml)