Monoclonal antibody CD4

antibodyfor histopathologyimmunohistochemistry

Antigen Background
The CD4 molecule (T4) is a single-chain transmembrane glycoprotein of approximately 59 kD. CD4 is expressed on a subset of T cells (helper/inducer), representing about 45% of peripheral blood lymphocytes, and at lower levels on monocytes and germinal center macrophages. Most cases of cutaneous T-cell lymphoma, including mycosis fungoides, express CD4; HTLV-1–associated adult T-cell leukemia/lymphoma is also generally CD4 positive.

Disclaimer
CD4 is recommended for detection of specific antigens of interest in normal and neoplastic tissues as an adjunct to conventional histopathology using non-immunologic histochemical stains.

Products

• CD4-368-L-CE — 1ml NCL-L-CD4-368
  • Clone: 4B12
  • Pathology Menu: Hematopathology
  • Configuration: Liquid Concentrate
  • HD (High Definition): Yes
  • Use: P (HIER)
  • Source: Monoclonal
  • Species: Mouse
  • Regulatory Status: In Vitro Diagnostic Use
  • Volume: 1ml
• PA0427 — 7ml CD4 (4B12) Bond RTU Primary
  • Clone: 4B12
  • Pathology Menu: Hematopathology
  • Configuration: BOND RTU
  • HD (High Definition): Yes
  • Use: P (HIER)
  • Source: Monoclonal
  • Species: Mouse
  • Regulatory Status: In Vitro Diagnostic Use
  • Volume: 7ml
• CD4-368-L-U — 1ml NCL-L-CD4-368
  • Clone: 4B12
  • Pathology Menu: Hematopathology
  • Configuration: Liquid Concentrate
  • HD (High Definition): Yes
  • Use: P (HIER)
  • Source: Monoclonal
  • Species: Mouse
  • Regulatory Status: In Vitro Diagnostic Use
  • Volume: 1ml
• PA0427-U — 7ml CD4 (4B12) Bond RTU Primary
  • Clone: 4B12
  • Pathology Menu: Hematopathology
  • Configuration: BOND RTU
  • HD (High Definition): Yes
  • Use: P (HIER)
  • Source: Monoclonal
  • Species: Mouse
  • Regulatory Status: In Vitro Diagnostic Use
  • Volume: 7ml

Replaces

• CD4-1F6
• CD4-1F6-CE
• CD4-1F6-CE-S
• CD4-1F6-L-CE
• CD4-1F6-O
• CD4-1F6-R-7
• CD4-1F6-R-7-CE
• CD4-1F6-S
• CD4-368
• CD4-368-L
• CD4-368-L-A
• CD4-368-L-CE-S
• CD4-368-L-S
• CD4-368-S
• CD4-368-L-CE-H
• CD4-368-L-H
• PA0368

Available Documents (per SKU)

• SDS (safety data sheet) available for SKUs where provided
• IFU (instructions for use) available for SKUs where provided

Technical characteristics

• Clone: 4B12
• Pathology Menu: Hematopathology
• Use: P (HIER)
• Configuration: Liquid Concentrate or BOND RTU (depends on SKU)
• HD (High Definition): Yes
• Source: Monoclonal
• Species: Mouse
• Regulatory Status: In Vitro Diagnostic Use
• Available Volumes: 1ml (Liquid Concentrate) and 7ml (BOND RTU)
• Available SKUs/Variants: CD4-368-L-CE, PA0427, CD4-368-L-U, PA0427-U