Tomography test phantom Hoffman 3D

for nuclear imagingfor MRIbrain

Overview: The Hoffman 3D brain phantom is a reference anatomical phantom designed for realistic three-dimensional simulation of the human brain. It accurately reproduces the relative distribution of gray matter, white matter and ventricles as observed in clinical brain imaging. The phantom is built from a precisely machined stack of slices to simulate a gray/white matter activity ratio of 4:1 via partial-volume effects. A single fillable chamber simplifies preparation while ensuring homogeneous activity distribution. Ventricles are represented as non-active regions.

Main applications:

• Evaluation of acquisition and reconstruction methods in brain imaging
• Validation of 3D reconstruction algorithms
• Study of attenuation and scatter effects
• Assessment of SPECT/PET/MRI registration
• Research and development

Anatomical simulation:

• Realistic three-dimensional representation of the human brain
• Simulated gray/white matter ratio: 4:1
• Ventricles modeled as non-active areas
• Simulation achieved by partial-volume effect

Construction:

• Cylindrical phantom body in PMMA
• Brain inserts in polycarbonate
• Stacking of 19 anatomically machined sections

Dimensions:

• Inner cylinder diameter: approx. 208 mm
• Inner cylinder height: approx. 175 mm
• Fillable volume: approx. 1.2 L

Slice thickness:

• Top slice: approx. 3.1 mm
• Central slices: 6.5 mm
• Bottom slice: approx. 9.7 mm

Modalities compatibility:

• SPECT
• PET
• MRI

Options and additional features: Optional solid defects can be included to simulate localized anomalies, notably within the deep gray nuclei, for detection assessment and reconstruction effect evaluation.

Characteristics / technical specifications:

• Model: BR/3D/P - Hoffman 3D brain phantom
• Materials: PMMA cylinder, polycarbonate brain inserts
• Number of anatomical sections: 19
• Gray/white matter ratio: 4:1 (simulated by partial-volume effect)
• Ventricles: non-active regions
• Inner diameter: ~208 mm
• Inner height: ~175 mm
• Fillable volume: ~1.2 L
• Slice thicknesses: top ~3.1 mm / central 6.5 mm / bottom ~9.7 mm
• Compatibility: SPECT, PET, MRI