DNA library preparation reagent 09052143001

for DNA sequencingfor nucleic acidsNGS

Overview
Design Share panels are NGS target enrichment designs developed by Roche scientists in collaboration with leading researchers. They combine pre-designed content from research experts, KAPA probe design expertise and performance data. Design Share panels provide a convenient entry into NGS target enrichment and are fully customizable using the HyperDesign Tool to add or remove content to suit specific research needs.

Available panels

• Somatic oncology research: KAPA HyperCap DS NHL Panel
• Hereditary genetics and oncology research: KAPA HyperCap DS Inherited Disease Panel; KAPA HyperCap DS Sudden Cardiac Death Panel; KAPA HyperCap DS NeuroDegeneration Panel; KAPA HyperCap DS Hereditary Cancer Research Panel
• Metabolic disease research: KAPA HyperCap DS Human mtDNA Design

Design Share panels comparison overview (selected items)

• KAPA HyperCap DS NHL Panel | Somatic oncology research | Human | HG38 | Covers 383 genes and regions commonly associated with B-cell lymphomas; capture target size 341 Kb | KAPA HyperChoice MAX 3Mb T1 | IRN 1000028225 | Material numbers: 09052593001 (24 rxn); 09052615001 (96 rxn)
• KAPA HyperCap DS Inherited Disease Panel | Hereditary genetics & oncology research | Human | HG38 | Covers >4100 genes and regions associated with inherited disease; capture target size 12.3 Mb | KAPA HyperChoice Probes / KAPA HyperChoice MAX 40Mb | IRN 1000004873 | Material numbers: 09053352001 (24 rxn); 09053379001 (48 rxn); 09053387001 (96 rxn); 09053395001 (192 rxn); 09053409001 (384 rxn)
• KAPA HyperCap DS Sudden Cardiac Death Panel | Hereditary genetics & oncology research | Human | HG38 | Covers 152 genes/regions associated with cardiovascular conditions; capture target size 772 Kb | KAPA HyperChoice Probes / KAPA HyperChoice MAX 3Mb T3 | IRN 1000004863 | Material numbers: 09052895001 (12 rxn); 09052909001 (24 rxn); 09052917001 (48 rxn); 09052925001 (96 rxn); 09052933001 (192 rxn); 09052941001 (384 rxn)
• KAPA HyperCap DS NeuroDegeneration Panel | Hereditary genetics & oncology research | Human | HG38 | Covers >98 genes/regions associated with neurodegenerative disorders; capture target size 335 Kb | KAPA HyperChoice Probes / KAPA HyperChoice MAX 3Mb T1 | IRN 1000004883 | Material numbers: 09052585001 (12 rxn); 09052593001 (24 rxn); 09052607001 (48 rxn); 09052615001 (96 rxn); 09052623001 (192 rxn); 09052631001 (384 rxn)
• KAPA HyperCap DS Hereditary Cancer Research Panel | Hereditary genetics & oncology research | Human | HG19 | Covers 226 genes and regions commonly associated with hereditary cancer syndromes; capture target size 744 Kb | KAPA HyperChoice Probes / KAPA HyperChoice MAX 3Mb T3 | IRN 1000007813 | Material numbers: 09052895001 (12 rxn); 09052909001 (24 rxn); 09052917001 (48 rxn); 09052925001 (96 rxn); 09052933001 (192 rxn); 09052941001 (384 rxn)
• KAPA HyperCap DS Human mtDNA Design | Metabolic disease research | Human | HG38 | Covers the human mitochondrial genome; primary target size ~16 Kb | KAPA HyperChoice Probes / KAPA HyperChoice MAX 0.5Mb T1 | IRN 1000005603 | Material numbers: 09052143001 (12 rxn); 09052151001 (24 rxn); 09052160001 (48 rxn); 09052178001 (96 rxn); 09052186001 (192 rxn); 09052194001 (384 rxn)

Notes
For Research Use Only (RUO). Not for use in diagnostic procedures. Performance data available per panel.

Technical specifications

• Product name: Design Share Panels
• Commercial name / model: Design Share Panels
• Product family / brand: KAPA
• Intended use: Research Use Only (RUO) — not for diagnostic procedures
• Product types: Predesigned NGS panels; NGS reagents and accessories
• Techniques: Targeted sequencing; Next-generation sequencing (NGS)
• Applications: Target enrichment (probe panels)
• Genome builds referenced: HG19, HG38 depending on panel
• Capture target sizes: Range from ~16 Kb (mtDNA) to multi-Mb panels (examples above)
• Pack sizes / material numbers: Multiple pack sizes per panel (examples listed above)
• Ordering identifiers: Internal references (IRN) provided per panel (examples listed above)
• Customizability: Panels are fully customizable using the HyperDesign Tool to add/remove content
• Performance: Performance data available per panel
• Related product families: KAPA HyperChoice MAX, KAPA HyperChoice Probes, KAPA HyperCapture Reagent Kits, KAPA HyperCapture Bead Kits