Real-time DNA amplification system cobas® 8800

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Overview
The cobas® 8800 system integrates and fully automates PCR-based nucleic acid testing (NAT) workflows for high-volume molecular diagnostics. It provides high throughput, rapid time-to-result and extended walk-away capability to improve laboratory throughput and operational efficiency. Designed for in vitro diagnostic (IVD) use.

Key benefits

• Complete automation with random sample loading and long walk-away times to minimize manual interventions
• High throughput and fast time-to-results to support large testing volumes
• Pre-calibrated, ready-to-use reagents to simplify handling and reduce errors
• Onboard storage and refrigeration for reagents and consumables to decrease loading frequency
• End-to-end traceability from sample to result using RFID and barcode-tagged consumables
• Automated intelligent scheduling with continuous assembly of optimal runs to reduce sample idling
• Priority lane options to expedite urgent assays and samples
• Ability to run IVDs and LDTs simultaneously and support for open-channel assays via the cobas® omni utility channel

Integration & data
Supports integration with pre-analytical automation (e.g., cobas® prime and cobas® p 612), Navify® Lab Operations and Navify® Analytics for operational control, pre-analytics and actionable insights.

System components & workflow

• Sample supply: continuous loading of sample racks (primary and/or secondary tubes)
• Sample transfer: automated barcode scanning and transfer to processing plates
• Sample preparation: extraction and purification of nucleic acids in the processing module
• Amplification and detection: automated amplification and real-time PCR detection
• Inventory manager: onboard storage for reagents, controls and consumables enabling full automation
• Cross-contamination prevention: hydraulic doors, airlock screens, separation of pipetting, automatic heat sealing and AmpErase usage

Performance summary (representative)
Up to 1,056 results in 8 hours; up to 4,128 results in 24 hours.
Walk-away time: up to 4 hours.
Maximum number of tests per run: 96.
Assay reagent cassette capacity: up to 12.
Up to 6 unique assays per run for testing flexibility.

Regulatory / Intended use
For in vitro diagnostic (IVD) use.

Technical specifications

• Model: cobas® 8800 system (Software 2.0)
• Typical maximum throughput: up to 1,056 results per 8 hours (up to 4,128 per 24 hours)
• Walk-away time: up to 4 hours (dependent on workload)
• Maximum number of tests per run: 96
• Unique assays per run: up to 6
• Assay reagent cassette capacity: up to 12
• Traceability: RFID and barcode-tagged reagents and consumables
• Automation features: pre-calibrated reagents, onboard refrigeration, automated scheduling, priority lane for urgent samples
• Open channel support: cobas® omni utility channel for automated open-channel assays
• Integration: compatible with cobas® prime, cobas® p 612 pre-analytical systems, Navify® Lab Operations and Navify® Analytics
• Intended use: In vitro diagnostic (IVD)