Allergen-specific IgE reagent kit

solutionIgEgenetic

(IgE) has a high affinity for basophils and mast cells, so it is also called reagin or cytophilic antibody. IgE is mainly produced by the plasma cells of the lamina propria of the respiratory tract and digestive tract mucosa, and its content is extremely low in the blood of normal people, accounting for about 0.002% of the total serum Ig. IgE is related to type I allergy. In patients with allergic constitution or hypersensitivity, the serum IgE is significantly higher than that of normal people, so the high level of IgE in serum often indicates the existence of genetic allergy or type I allergy. oduct Advantage SUMMARY AND EXPLANATION OF THE TEST IgE is one of the body's 5 classes (isotypes) of immunoglobulins (antibodies).Like other immunoglobulins, IgE is produced by B cells and plasma cells. In contrast to other immunoglobulins, the concentration of IgE in the circulation is very low. Immunoglobulin E in cord blood usually measures less than 1 U/mL (1 U = 2.4 ng). Generally, adult IgE levels are achieved by 5 to 7 years of age. Between the ages of 10 and 14 years, IgE levels may be higher than those in adults. After age 70 years, IgE levels may decline slightly and be lower than the levels observed in adults younger than 40 years. Circulating IgE concentrations are very low because mast cells have a very high affinity for IgE (1010 mol/L−1) via their -heavy-chain Fc receptors (FcER).