Solution reagent kit DR1049

proteincystatin Ccreatinine

The kit has been designed for the quantitative determination of Cystatin C (Cys-C) in human serum. The method can be used for samples over the range of 0.01-6.00 μg/mL. Product Description SUMMARY AND EXPLANATION OF THE TEST Cystatin C (Cys-C) detection kit (CLIA) (hereinafter referred to as the kit), is used for the in vitro quantitative determination of cystatin C (Cys-C) concentration in human serum, which is an important indicator to assess renal function in kidney transplant . Cancer treatment can damage kidney function, and therefore Cystatin C is used as an early indicator of renal damage. It is used to adjust the dose to prevent irreversible kidney damage. Lower protein intake in cancer patients or muscle consumption can prevent increased creatinine levels of renal failure. Therefore, cystatin C assay provides important information for renal function. Cystatin C is a kind of cysteine protease inhibitor, also known as γ--trace protein and post-γ- globulin, widely presents in nucleated cells and body fluids in various tissues. It is a kind of non-glycosylated protein of low molecular weight coded by the CST3 gene. Its molecular weight is 13.3KD, comprising 122 pcs of amino acid residues, which can be generated by all nucleated cells with a constant rate. Circulating cystatin C will be cleared by glomerular filtration, and reabsorbed by proximal tubule, but then all the reabsorbed Cys-C will be metabolic broke down, and do not return to the blood. And therefore Cys-C concentration in the blood is determined by glomerular filtration without relying on any external factors, such as gender, age, diet,