Gastrointestinal disease detection kit DR1055

for ovarian cancerfor tumor markersserum

Cancer antigen 72-4 (CA 72-4), which is also known as carbohydrate antigen, is identified as a serum tumor biomarker (threshold of approximately 4.6 U/mL in serum), which allows the suspicion of cancer. CA 72-4 is an antigenic determinant of tumor-associated glycoprotein 72 (TAG-72) glycoprotein, which is a 48-kDa mucin-like glycoprotein complex. CA 72-4 is defined by two monoclonal antibodies (CC 49 and B72-3) and has been found in a wide range of human adenocarcinomas such as colorectal, gastric, lung, breast, and ovarian cancer, with reported sensitivities of up 50% and an overall specificity of over 95%. However, it is rarely expressed in benign and normal adult tissues. Measurement of CA 72-4 has also shown good correlation with disease burden and is predictive of disease recurrence. Product Description Cancer antigen 72-4 (CA72-4) is a tumor-associated-glycoprotein (TAG-72) used as a tumor marker for gastrointestinal and ovarian cancers. Elevated CA72-4 levels in serum and plasma are seen in the pancreas, gallbladder, colon, cervix, and endometrium carcinomas. There is a correlation between serum CA72-4 levels and tumor stage/size compared to other commonly used biomarkers. CA72-4 is also an independent marker for the therapeutic monitoring and care of ovarian cancer patients who are CA125 negative. [INTENDED USE] The kit has been designed for the quantitative determination of Carbohydrate antigen 72-4 (CA72-4) in human serum. The method can be used for samples over the range of 0-200U/mL The method can be used for samples over the range of 0-200U/mL.The test has to be performed on the CIA fully auto analyzer (Including CIA 600, CIA 1200, CIA 1800, CIA2800).