CLIA Thyrotropin Receptor Antibody TRAb IVD Products for Chemiluminescent Immunoassay in Thyroid.
The kit has been designed for the quantitative determination of TSH Receptor Antibody (TRAb) in human serum. The method can be used for samples over the range of 0.08-30IU/L.
Product Description
TRAb detection kit (CLIA) (hereinafter referred to as the kit) is used for the in vitro quantitative determination of TRAbconcentration in human serum, which is mainly for diagnosis of Graves disease. TRAb is a kind of IgGsecreted by lymphocytes, and its corresponding antigen is the membrane surface part of thyroid cells near TSH receptor.When TRAb binds with the thyroid cells, it will be activated; resulting in thyroid function is stimulated, causing hyperthyroidism and goiter.Its role resembles TSH. It is not controlled by the negative feedback control system, which results in clinical symptoms of hyperthyroidism of Graves’s disease.
TRAb indications include: 1. Autoimmune hyperthyroidism diagnosis and troubleshooting, as well as multi-functional autonomous thyroid nodular goiter. Because Graves disease treatment different from other treatment of hyperthyroidism, so the initial TRAb measurement is very useful. 2. Monitoring Graves' disease treatment and recurrences, and has important significance for clinical management. Graves disease during treatment with antithyroid drugs often TRAb concentration decreased after medical treatment TRAb low concentration or disappearance may indicate remission, termination of treatment may be considered. 3. TRAb measured the last three months of pregnancy.