Laboratory workstation for the pharmaceutical industry FLEX SWILE

fully automatedfloor-standingmodular

Overview
Solid compound distribution into formulation screening plates is often manual, time-consuming, repetitive and error-prone; fractional compositional mapping in the μg/mg range is typically not achievable manually. The SWILE technology provides a fully automated one-to-one gravimetric pick & decision dispense of compounds from μg to mg. The technology is based on Chemspeed’s proprietary overhead gravimetric dispensing tool design combined with a second analytical on-deck balance. Disposable glass tips are used to eliminate cross-contamination; these are stored and provided by the SWIN dispenser. SWINs are available in different diameters and can be adjusted according to the desired target amount. A tilt/shake rack is used to loosen and tilt solids prior to pick-up.

Key features

• Decision dispensing for high accuracy and precision
• Dispensing range: hundreds of μg up to ≈5 mg with ±10 μg resolution
• Disposable glass tips to avoid cross-contamination
• No dead volume
• Unattended operation
• Fully inert glass contact surfaces

Workflow (example)

• Read barcode of source vial
• Transport source vial to tilt/shake rack
• Loosen solid compound (tilt/shake)
• Gravimetric pick & dispense into solubility/formulation plates

Benefits

• Proprietary robotic tool exchange interface
• Ventilated hood option for safe, conditioned operation; trolley available
• Optimized footprint (~3x3 ft, 90x90 cm) offering high capacity vs. space
• SWILE robotic tool can be combined with other tools for multi-workflow integration
• On-deck analytical balance, tilt/shake rack, barcode reader, multigripper support
• AUTOSUITE software for experiment design, execution and analysis
• Interfaces for DOE/ML/AI/LIMS/ELN integration

Technical specifications

• Technology: true one-to-one gravimetric pick & decision dispense
• Dispensing range: hundreds of μg up to ≈5 mg
• Resolution / repeatability: ±10 μg (decision dispensing)
• Tip type: disposable inert glass tips to prevent cross-contamination
• SWIN dispenser: provides and stores disposable glass tips; SWINs available in multiple diameters
• Auxiliary hardware: on-deck analytical balance, tilt/shake rack, barcode reader, multigripper
• Operation: unattended workflow capability
• Footprint: ~3x3 ft (90x90 cm)
• Environment: ventilated hood option
• Software: AUTOSUITE; interfaces for DOE/ML/AI/LIMS/ELN
• Applications: formulation screening, fractional compositional mapping for cathode materials, optoelectronics, solubility-plate dispensing and drug product distribution