Automation system for the pharmaceutical industry SciYbotic

for quality controlrobotized

Overview
The SciYbotic / Chemspeed FLEX TT (TT-IR configuration) is an automated at-line solution for oral solid dosage (OSD) quality control. The system integrates a Bruker MPA FT-NIR Multi Purpose Analyzer and is designed to transfer validated laboratory methods to production environments while supporting GLP/GMP operations.

Key Functional Components

• Robotic arm for precise tablet handling and positioning: automated pick-and-place with repeatable orientation control.
• Integrated sensing and vision:
  • 2D vision
  • 3D vision
  • FT-NIR spectroscopy (Bruker MPA)
• synTQ control platform: centralized control, real-time insight, knowledge management and support for advanced control strategies; compliant with 21 CFR Part 11 and data integrity principles.
• Analytical and chemometric integration: validated lab methods and chemometric models can be deployed in production for assay and content uniformity testing.
• Multi-modal testing capability: configurable tests for weight, thickness, hardness, content uniformity and assay.
• Tablet traceability: uniquely marked trays that maintain individual tablet traceability linked to synTQ database; optional external digital platform integration for extended data storage.

Benefits

• Enables at-line QC and method transfer from lab to production, applicable to batch and continuous manufacturing.
• Supports regulatory compliance workflows (GLP/GMP) and 21 CFR Part 11 requirements via synTQ.
• Combines robotics, vision and FT-NIR to automate multiple physical and chemical tablet tests in a single platform.

Technical specifications

• Product family / model: SciYbotic / Chemspeed FLEX TT (TT-IR configuration integrates Bruker MPA FT-NIR Multi Purpose Analyzer)
• Measurement capabilities: tablet weight, thickness, hardness, content uniformity, assay
• Analytical hardware integration: Bruker MPA FT-NIR integrated (TT-IR)
• Control software: synTQ control platform; real-time insight, knowledge management and advanced control strategies
• Compliance: designed for GLP and GMP environments; synTQ supports 21 CFR Part 11 and data integrity principles
• Robotics & vision: robotic arm for handling and positioning; 2D vision; 3D vision
• Traceability: uniquely marked, fully traceable trays; data traceability in synTQ database; optional integration with external digital platforms
• Deployment: at-line testing enabling method transfer from lab to production; suitable for batch and continuous manufacturing
• Use cases: oral solid dosage (OSD) quality control, at-line QC