Automatic sample preparation system FLEX AUTOPLANT

automatedfor researchfor research and development

Overview
Chemspeed and Bruker combine advanced automation with real‑time online NMR analytics to provide an end‑to‑end platform for process research and chemical development. The FLEX AUTOPLANT automates reaction preparation, synthesis, sampling, work‑up and iterative analysis to accelerate development cycles, reduce manual operations and deliver consistent analytical insight via integrated online NMR monitoring.

Key features

• Real‑time online NMR reaction monitoring for data‑driven decision making.
• High‑throughput process R&D and chemical development via automated reaction prep, dispensing, synthesis and analysis.
• Workflows designed around Quality by Design (QbD) and proven acceptable range (PAR) methodologies.
• Minimized manual intervention to improve safety, reproducibility and operational efficiency.
• Seamless integration with benchtop and high‑field Bruker NMR instruments for flexible analytical paths.

Workflow components (FLEX AUTOPLANT example)

• Solid dispensing
• Liquid dispensing
• Mixing with control of temperature, pressure, gas and liquid feeds
• Work‑up (sample processing and preparation)
• Analysis (LC, NMR, UV‑VIS, IR, Raman) including online benchtop NMR monitoring

Benefits

• Accelerated, data‑driven process development using continuous online NMR feedback.
• Increased throughput for process R&D and chemical development campaigns.
• Robust, reproducible optimization using QbD and PAR‑based workflows.
• Reduced hands‑on operations, improving laboratory safety and consistency.
• Flexible analytical strategy through integration with benchtop and high‑field Bruker NMR systems.

Technical specifications / characteristics

• Brand: Chemspeed
• Solution name: Automated Process Research / Chemical Development with Online NMR Analysis
• Model / Platform: FLEX AUTOPLANT
• Integrated analytics partner: Bruker (benchtop and high‑field NMR)
• Automated capabilities: reaction preparation, solid/liquid dispensing, mixing (temperature/pressure/gas/liquid feeds), sampling, work‑up, iterative analysis
• Supported analyses: LC, NMR, UV‑VIS, IR, Raman (online and offline)
• Workflow approach: Quality by Design (QbD) and PAR‑driven
• Typical use cases: process research, chemical development, preparative synthesis, reaction work‑up, analytical evaluation
• Multimodal integration: supports online and offline benchtop NMR monitoring
• Media: supporting product video available