Fully automated sample preparation system FLEXSHUTTLE

laboratoryfor drug discoverybiological

Overview
FLEXSHUTTLE by Chemspeed is a modular, end-to-end automated platform for drug discovery workflows. It orchestrates synthesis, purification, chemical analysis and biological testing within a single expandable system, and integrates a standardized consumables concept (SMOLE) to streamline medicinal chemistry operations.

Key capabilities

• Automated synthesis, purification, chemical analysis and biological testing in integrated E2E workflows
• Modular architecture enabling scalable throughput and configurable workflows
• Support for Design–Make–Test–Analyze (DMTA) automation and data export
• Compatibility with SMOLE consumables for standardized sample handling

Features / Example functionalities

• Customizable laboratory layout and automated shuttle navigation
• Workflow modeling, execution and centralized control
• Use of SMOLE pins and consumables for simplified sample transfers
• Integration points for SPEEDCHEM, CATSCREEN and other instruments

Generic workflow steps (end-to-end drug discovery)

• Reaction preparation
• Synthesis
• Purification
• Chemical testing (e.g., UPLC‑MS, NMR, UV‑Vis)
• Biological testing
• Data export and orchestration

Detailed example workflow steps / modules observed on the page

• Load MTP (microtiter plate) with empty SMOLE pins
• Reaction preparation (SMOLE PIN)
• Load MTP with empty vials and add SMOLE pins
• SPEEDCHEM and CATSCREEN integration steps
• Reaction work-up and purification modules
• NMR, UPLC‑MS, evaporation modules
• UV‑Vis absorbance, fluorescence, molecular weight and particle size analysis
• Export data

Benefits

• Accelerates the Design–Make–Test–Analyze cycle for drug discovery
• Increases throughput while reducing material consumption and waste
• Improves reproducibility and data quality
• Enables laboratory digitalization and frees skilled staff for higher‑value tasks

Technical specifications

• Marque: Chemspeed
• Denomination commerciale: FLEXSHUTTLE
• Purpose: automated end-to-end drug discovery workflows (Design–Make–Test–Analyze)
• Architecture: modular, expandable system for scalable throughput and configurable workflows
• Consumables concept: SMOLE technology (standardized chemical consumables and SMOLE pins)
• Supported modules / integrations (examples): SPEEDCHEM, CATSCREEN, NMR, UPLC‑MS, purification modules, evaporation, UV‑Vis, fluorescence, molecular weight and particle size analysis
• Data: workflow orchestration and data export capabilities
• Target users: drug discovery teams, medicinal chemistry, R&D and QC laboratories