Fully automated sample preparation system FLEX CATSCREEN

roboticfor the pharmaceutical industrydosing

Overview
Unattended catalyst preparation and screening at ambient and elevated pressure in versatile 96-well plates using disposable glass vials/reactors. Suitable for standardized, automated workflows and data logging.

Product summary
The FLEX CATSCREEN (Chemspeed) integrates patented overhead gravimetric dispensing with a fully automated MTP pressure block and AUTOSUITE software to accelerate, standardize and digitalize catalyst synthesis and screening in flexible well-plate formats (12x20 mL, 24x8 mL, 48x2 mL, 96x1 mL total vial volume).

Workflow (FLEX CATSCREEN)

• Add catalyst
• Add solvent/additives
• Add solid or liquid into vials on the MTP
• Shake
• Apply pressure (1-100 bar)
• Shake and heat (CATSCREEN)
• Transfer MTP to tray
• Work-up (filtration, sampling)

Benefits

• Preparation and screening at ambient and elevated pressure (1–100 bar) in 96-well glass vial formats with automated work-up and analysis
• Ventilated hood option for inert atmosphere and operator safety
• Compact footprint (~90 x 90 cm) for reduced costs and improved ROI
• Fully automated MTP pressure block with automated opening/closing and plate handling
• 4-needle head for volumetric liquid handling and sampling
• Patented overhead gravimetric solid dispensing into multiple vial/plate/reactor formats
• Balance moves to destination to increase speed and efficiency
• Balance resolution options: 0.1 mg or 0.01 mg
• Dispensing range from milligrams up to several grams
• Powder dispensing robotic tool compatible with other tools for diverse workflows
• Automatic logging of dispensed amount, mixing speed, temperature, pressure, time, etc., in a read-only log file
• Exchangeable robotic tools to support multiple workflows
• AUTOSUITE software: drag & drop experiment design with interfaces to DOE, ML/AI, LIMS, ELN, ERP

Technical specifications

• Model/workflow name: FLEX CATSCREEN
• Vendor/brand: Chemspeed
• Supported well-plate formats (glass vials): 12x20 mL, 24x8 mL, 48x2 mL, 96x1 mL (total vial volume)
• Pressure capability: ambient up to 1–100 bar (MTP pressure block)
• Automated MTP pressure block with automated opening/closing and plate loading/unloading
• Overhead gravimetric dispensing/dosing (patented)
• Gravimetric balance resolution: 0.1 mg or 0.01 mg
• Dispensing range: from a few milligrams up to several grams
• 4-needle head for volumetric liquid handling and sampling
• Ventilated hood available for inertization and safety
• Optimized footprint: approx. 3 x 3 ft (90 x 90 cm)
• Compatible with disposable glass vials/reactors
• Supports automated work-up steps: filtration, sampling, transfer to trays
• Data logging: read-only log file capturing dispensed amount, mixing speed, temperature, pressure, time
• Exchangeable robotic tools to support multiple workflows
• Software: AUTOSUITE with integration to DOE, ML, AI, LIMS, ELN, ERP