Fully automated sample preparation system SWING MEDTECH

laboratorymixingmodular

Overview
Overhead gravimetric solid dispensing and user-friendly software enable automatic dispensing of virtually any powder or solid into a wide range of destinations (vials, tubes, plates, reactors, racks) without moving the destination, followed by mixing and microwave-assisted baking for bone cement / putty tube workflows.

Workflow (SWING MEDTECH)

• GAMP5, CFR 21 Part 11 compliance
• Dispense TCP (1–4 g)
• Dispense TCP (1–4 g) (repeat/parallel step)
• Transfer to robotic handling/transfer station
• Cover putty tubes and turn
• Mix or transfer to mixer and mix
• Turn and uncover putty tubes
• Pre-compress (rotation and distance controlled)
• Transfer baking beaker to microwave (MW)
• Transfer baking beaker to rotating unit
• Post-compress
• Return to rack; sort out nonconforming putties upon operator inspection

Benefits

• Decrease in cost per sample up to 90+ %
• Increase in productivity by a factor of 10+
• Gravimetric solid dispensing for low-density, sticky powders, any particle size, spherical or granulate shapes, beads and tablets into many rack/reactor formats
• The balance moves to the destination, increasing speed and efficiency
• Balance resolution options: 1 mg, 0.1 mg, 0.01 mg
• Large dispensing range: from a few mg up to several grams
• Powder dispensing robotic tool can be combined with other tools to support multiple workflows
• Dispensed amount, mixing speed, temperature, time and other parameters are stored in a read-only log file
• Exchangeable robotic tools to accommodate multiple workflows
• AUTOSUITE SOFTWARE — drag & drop experiment design with easy interface to data analysis
• Interface to DOE, LIMS, ELN, ERP

Software & Integration
AUTOSUITE enables fast, flexible experiment automation: design, execute, analyze and report experiments via drag & drop workflows. Orchestration tools support multi-system lab coordination and integration with laboratory informatics systems.

Technical specifications

• Application example: automated preparation of bone cement / putty tube workflows
• Gravimetric solid dispensing / dosing (overhead balance that moves to destination)
• Support for low-density, sticky powders, any particle size, spherical/granulate shapes, beads, tablets
• Destinations supported: vials, tubes, plates, reactors and various rack formats
• Balance resolution options: 1 mg, 0.1 mg, 0.01 mg
• Dispensing range: from a few milligrams up to several grams
• Mixing and transfer capabilities: robotic transfer to mixers, rotating units, microwave baking stations
• Microwave-assisted baking suitable for GMP/GLP environments
• Data logging: read-only log file recording dispensed amounts, mixing speed, temperature, time, etc.
• Compliance features: GAMP5 and CFR 21 Part 11 compatible workflows
• Exchangeable robotic tools and modular combinations to support multiple workflows
• Software integration: AUTOSUITE; interfaces to DOE, LIMS, ELN, ERP